Wiskott-Aldrich Syndrome Protein Family

A family of microfilament proteins whose name derives from the fact that mutations in members of this protein family have been associated with WISKOTT-ALDRICH SYNDROME. They are involved in ACTIN polymerization and contain a polyproline-rich region that binds to PROFILIN, and a verprolin homology domain that binds G-ACTIN.

Also Known As:

WAS Protein Family, Member 1; WAS Protein Family, Member 2; WAS Protein Family, Member 3; WASF1 Protein; WASF2 Protein; WASF3 Protein; WASP Protein Family; WAVE1 Protein; WAVE2 Protein; WAVE3 Protein; Wiskott-Aldrich Syndrome Protein Family, Member 1; Wiskott-Aldrich Syndrome Protein Family, Member 2; Wiskott-Aldrich Syndrome Protein Family, Member 3; WASP Family Verprolin Homologous Proteins; Wiskott Aldrich Syndrome Protein Family; Wiskott Aldrich Syndrome Protein Family, Member 1; Wiskott Aldrich Syndrome Protein Family, Member 2; Wiskott Aldrich Syndrome Protein Family, Member 3; WAS Protein Family; WASP-Family Verprolin Homologous Proteins; WAVE Proteins

Macromolecular Substances: 97
- Polymers: 13529
  - Biopolymers: 836
    - Microfilament Proteins: 501
      - Wiskott-Aldrich Syndrome Protein Family: 72
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Cytoskeletal Proteins: 743
    - Microfilament Proteins: 501
      - Wiskott-Aldrich Syndrome Protein Family: 72

J E Bear Selected Research

J E Bear Research Topics

Disease

Drug/Important Bio-Agent (IBA)